Mesenchymal stem cells, implications for pain therapy
Elena Trallori
Carla Ghelardini
Lorenzo Di Cesare Mannelli
摘要：History and biology of mesenchymal stem cell (MSC):MSCs were firstly described around 1970s by Friedenstein and his collaborators as a subpopulation of colony forming, clonogenic, plastic adherent stromal bone marrow derived cells, with the capacity to regenerate other tissues (Murphy et al., 2013). Caplan (1991) proposed that these mesenchy-mal cells were "stem" because of their ability to differentiate to any lineage of mesodermal cells. The richest sources of MSCs are bone marrow and adipose tissue, but they can also be isolated from synovial fluid, periosteum, fetal organs, pla-centa, umbilical cord blood and amniotic fluid (Murphy et al., 2013; Sherman et al., 2015).
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论文发表日期：2019-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1915-1916 )