Cerebrospinal fluid neurogranin as a new player in prion disease diagnosis and prognosis
Anna Villar-Piqué1
Inga Zerr2
Franc Llorens3
1.Network Center for Biomedical Research in Neurodegenerative Diseases(CIBERNED), Institute Carlos Ⅲ, Ministry of Health,Hospitalet de Llobregat, Spain;Bellvitge Biomedical Research Institute(IDIBELL), Hospitalet de Llobregat, Spain2.Department of Neurology, Clinical Dementia Center and National Reference Center for CJD Surveillance, University Medical School,G(o)ttingen, Germany;German Center for Neurodegenerative Diseases(DZNE),G(o)ttingen, Germany3.Network Center for Biomedical Research in Neurodegenerative Diseases(CIBERNED), Institute Carlos Ⅲ, Ministry of Health,Hospitalet de Llobregat, Spain;Bellvitge Biomedical Research Institute(IDIBELL), Hospitalet de Llobregat, Spain;Department of Neurology, Clinical Dementia Center and National Reference Center for CJD Surveillance, University Medical School,G(o)ttingen, Germany
摘要：Neurogranin (Ng) and its role as Alzheimer's disease (AD) biomarker:Ng is a calmodulin-binding protein mainly expressed in cerebral structures such as the cortex,hippocampus and striatum.It is mainly located in the dendritic processes,particularly in post-synaptic compartments,but also in the cytosolic compartment,being likely involved in the regulation of the intracellular calcium-calmodulin signaling pathway (Represa et al.,1990).
机标关键词：
论文发表日期：2020-05-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 861-862 )