Harnessing the stem cell properties of pericytes to repair the brain
Jo-Maree Courtney
Brad A. Sutherland
摘要：Over the last ten years or so, it has become apparent that pericytes have the potential to differentiate into other cell types which may help in the repair and regeneration of tissue after injury. In fact, pericytes have been described as a precursor to mesenchymal stem cells. Their location at the interface between the microvasculature and the brain parenchyma means they are ideally positioned to initiate repair and regeneration in response to various factors. In this perspective, we will highlight how pericytes have stem cell potential alongside their role in regulating processes, such as angiogenesis and inflammation, and dis-cuss how pericytes could be harnessed to promote tissue repair in the brain (Figure 1).
机标关键词：
论文发表日期：2020-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1021-1022 )