Exosome-mediated crosstalk between microglia and neural stem cells in the repair of brain injury
Bo-Ru Hou
Cheng Jiang
Ze-Ning Wang
Hai-Jun Ren
摘要：Brain injury, especially that caused by stroke, is a leading cause of mor-bidity and mortality worldwide. Numerous studies on the neuropro-tective effects of neural stem cells (NSCs) after brain injury have shown that crosstalk among neural cells, including neuron–glial, glial–glial, NSC–neuronal and NSC–glial communication, plays a major role in post-injury repair. Therefore, a better understanding of the factors in-volved in the interactions between NSCs and other neural cells should advance the development of therapeutic strategies for brain injury. In this article, we discuss the role of exosomes in the crosstalk between NSCs and microglia, focusing on key exosomal proteins and microR-NAs in brain injury progression and repair.
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论文发表日期：2020-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1023-1024 )