Non-pharmacological interventions for Parkinson's disease mild cognitive impairment: future directions for research
Davide Maria Cammisuli1
Roberto Ceravolo2
Ubaldo Bonuccelli2
1.Neurology Clinic,Department of Clinical and ExperimentalMedicine,University of Pisa,Pisa,Italy;Clinical Psychology,Psychophysiology and ClinicalNeuropsychology Laboratory,Department of Medicine andSurgery,University of Parma,Parma,Italy2.Neurology Clinic,Department of Clinical and ExperimentalMedicine,University of Pisa,Pisa,Italy
摘要：Parkinson's disease-mild cognitive impairment (PD-MCI) currently represents a valid diagnostic clinical entity with potential interest for therapeutic purpose. MCI is present in approximately 25–30％ of non-demented patients with PD (Weintraub et al., 2018). Several risk factors are associated with Parkinson's disease dementia (PDD) occurrence, such as old age at onset, long disease duration, motor impair-ment and MCI (Nicoletti et al., 2019). Specifically, PD-MCI patients with a higher risk for conversion into PDD report specific neurocognitive deficits in semantic language, figure drawing/copying and visuospatial tasks (Vasconcellos et al., 2019). Thus, the implementation of strategies counteracting a more severe cognitive deterioration of PD-MCI patients is urgently required.
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论文发表日期：2020-09-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1650-1651 )