Spinal genesis of Mayer waves
George Zaki Ghali1
Michael George Zaki Ghali2
Emil Zaki Ghali3
1.United States Environmental Protection Agency, Arlington, VA, USA ;Department of Toxicology, Purdue University, West Lafayette, IN, USA2.Department of Neurological Surgery, Houston Methodist Hospital, Houston, TX, USA;Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, USA3.Department of Medicine, Inova Alexandria Hospital, Alexandria, VA, USA;Department of Cardiothoracic Surgery, El Gomhoureya General Hospital, Alexandria, Egypt
摘要：Variability in cardiovascular spectra was first described by Stephan Hales in 1733. Traube and Hering ini-tially noted respirophasic variation of the arterial pressure waveform in 1865 and Sigmund Mayer noted a lower frequency oscillation of the same in anesthetized rabbits in 1876. Very low frequency oscillations were noted by Barcroft and Nisimaru in 1932, likely representing vasogenic autorhythmicity. While the origins of Traube Hering and very low frequency oscillatory variability in cardiovascular spectra are well described, genesis mechanisms and functional significance of Mayer waves remain in controversy. Various theories have posited baroreflex and central supraspinal mechanisms for genesis of Mayer waves. Several studies have demonstrated the persistence of Mayer waves following high cervical transection, indicating a spinal capacity for genesis of these oscillations. We suggest a general tendency for central sympathetic neurons to oscillate at the Mayer wave frequency, the presence of multiple Mayer wave oscillators through-out the brainstem and spinal cord, and possible contemporaneous genesis by baroreflex and vasomotor mechanisms.
机标关键词：genesismayerspinalwaves
论文发表日期：2020-10-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：11( 1821-1831 )
英文信息