Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration
Francisco Bosch-Morell1
Victoria Villagrasa2
Teresa Ortega3
Nuria Acero4
Dolores Mu?oz-Mingarro5
M. Eugenia González-Rosende2
Encarna Castillo2
M. Amparo Sanahuja2
Pilar Soriano6
Isabel Martínez-Solís7
1.Biomedical Sciences Institute,Universidad Cardenal Herrera-CEU,CEU Universities,Alfara del Patriarca,Valencia,Spain;Department of Biomedical Sciences,Faculty of Health Sciences,Universidad Cardenal Herrera-CEU,CEU Universities,Alfara del Patriarca,Valencia,Spain2.Department of Pharmacy,Faculty of Health Sciences,Universidad Cardenal Herrera-CEU,CEU Universities,Alfara del Patriarca,Valencia,Spain3.Department of Pharmacology,Pharmacognosy and Botany,Universidad Complutense de Madrid,Madrid,Spain4.Department of Pharmaceutical and Health Sciences,Faculty of Pharmacy,Universidad San Pablo-CEU,CEU Universities,Madrid,Spain5.Department of Chemistry and Biochemistry,Faculty of Pharmacy,Universidad San Pablo-CEU,CEU Universities,Madrid,Spain6.ICBiBE-Botanical Garden,University of Valencia,Valencia,Spain7.Biomedical Sciences Institute,Universidad Cardenal Herrera-CEU,CEU Universities,Alfara del Patriarca,Valencia,Spain;Department of Pharmacy,Faculty of Health Sciences,Universidad Cardenal Herrera-CEU,CEU Universities,Alfara del Patriarca,Valencia,Spain;ICBiBE-Botanical Garden,University of Valencia,Valencia,Spain
摘要：The retina may suffer neurodegenerative damages, as other tissues of the central nervous system do, and serious eye diseases may develop. One of them is age-related macular degeneration, which causes progres-sive loss of vision due to retina degeneration. Treatment of age-related macular degeneration focuses on antioxidant agents and anti-vascular endothelial growth factor compounds, among others, that prevent/diminish oxidative stress and reduce neovascularisation respectively. The phytochemicals, medicinal plants and/or plant-diet supplements might be a useful adjunct in prevention or treatment of age-related macular degeneration owing to their antioxidant and anti-vascular endothelial growth factor properties. This review article presents the most investigated plants and natural products in relation to age-related macular degen-eration, such as saffron, ginkgo, bilberry and blueberry, curcuma or turmeric, carotenoids, polyphenols, and vitamins C and E. This study provides up-to-date information on the effects, treatments, safety and efficiency of these phytotherapy products.
机标关键词：
论文发表日期：2020-12-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：10( 2207-2216 )
英文信息