Microglia-associated neuroinflammation is a potential therapeutic target for ischemic stroke
Wan Zhang1
Tian Tian2
Shao-Xin Gong3
Wen-Qian Huang1
Qin-Yi Zhou1
Ai-Ping Wang1
Ying Tian1
1.Institute of Clinical Research,Affiliated Nanhua Hospital,University of South China,Hengyang,Hunan Province,China2.Department of Clinical Laboratory,the First Hospital of Changsha,Changsha,Hunan Province,China3.Department of Pathology,the First Affiliated Hospital of University of South China,Hengyang,Hunan Province,China
摘要：Microglia-associated neuroinflammation plays an important role in the pathophysiology of ischemic stroke. Microglial activation and polarization, and the inflammatory response mediated by these cells play important roles in the development, progression and outcome of brain injury after ischemic stroke. Currently, there is no effective strategy for treating ischemic stroke in clinical practice. Therefore, it is clinically important to study the role and regulation of microglia in stroke. In this review, we discuss the involvement of microglia in the neuroinflammatory process in ischemic stroke, with the aim of providing a better understanding of the relationship between ischemic stroke and microglia.
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论文发表日期：2021-01-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 6-11 )
英文信息