Intravitreal fluorogold tracing as a method to label retinal neurons and the retinal pigment epithelium
Francisco Javier Valiente-Soriano
Fernando Lucas-Ruiz
Juan A.Miralles de Imperial-Ollero
Manuel Vidal-Sanz
Marta Agudo-Barriuso
1.Departamento de Oftalmología,Facultad de Medicina,Universidad de Murcia and Instituto Murciano de Investigación Biosanitaria-Virgen de la Arrixaca (IMIB-Arrixaca) Murcia,Spain2.Departamento de Oftalmología,Facultad de Medicina,Universidad de Murcia and Instituto Murciano de Investigación Biosanitaria-Virgen de la Arrixaca (IMIB-Arrixaca) Murcia,Spain3.Departamento de Oftalmología,Facultad de Medicina,Universidad de Murcia and Instituto Murciano de Investigación Biosanitaria-Virgen de la Arrixaca (IMIB-Arrixaca) Murcia,Spain4.Departamento de Oftalmología,Facultad de Medicina,Universidad de Murcia and Instituto Murciano de Investigación Biosanitaria-Virgen de la Arrixaca (IMIB-Arrixaca) Murcia,Spain5.Departamento de Oftalmología,Facultad de Medicina,Universidad de Murcia and Instituto Murciano de Investigación Biosanitaria-Virgen de la Arrixaca (IMIB-Arrixaca) Murcia,Spain
摘要：Techniques to label the neuroretina and the retinal pigment epithelium (RPE) have been the topic of many studies for years. The reliability and reproducibility of these techniques are essential to investigate retinal alterations of ocular pathologies and possible treatments. In particular, the study of the integrity of the RPE is of great importance in pathologies such as retinitis pigmentosa or age-related macular degeneration (Gu et al., 2012;Fisher and Ferrington, 2018;Zhang et al., 2019). The most common approaches use antibodies to identify different cell populations. Recently, we have described a novel technique to study the integrity of the neuroretina and the RPE, as well as the functionality of the RPE in rats (Valiente-Soriano et al., 2020).
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论文发表日期：2021-10-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 2000-2001 )