It takes more than tau to tangle: using proteomics to determine how phosphorylated tau mediates toxicity in neurodegenerative diseases
Geoffrey Pires1
Eleanor Drummond2
1.Center for Cognitive Neurology, Department of Neurology, New York University School of Medicine, New York, NY, USA;Alzheimer's and Prion Diseases Team, Paris Brain Institute, CNRS, UMR 7225, INSERM 1127, Sorbonne University UM75, Paris, France2.Center for Cognitive Neurology, Department of Neurology, New York University School of Medicine, New York, NY, USA;Brain and Mind Centre and School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Australia
摘要：Two of the most common causes of dementia are Alzheimer's disease (AD) and frontotemporal dementia (FTD). AD is an irreversible, progressive neurodegenerative disorder that is clinically characterized by severe memory loss and behavioral impairment that eventually interferes with everyday function.
机标关键词：
论文发表日期：2021-11-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 2211-2212 )