A biophysical perspective on the unexplored mechanisms driving Parkinson's disease by amphetamine-like stimulants
Carla Ferreira1
Joana Couceiro2
Sandra Tenreiro3
Alexandre Quintas2
1.Molecular Pathology and Forensic Biochemistry Laboratory, Centro de Investiga??o Interdisciplinar Egas Moniz, P-2825-084 Caparica, Portugal;Laboratório de Ciências Forenses e Psicológicas Egas Moniz, Campus Universitário–Quinta da Granja, Monte de Caparica, P-2825-084 Caparica, Portugal;Faculty of Medicine of Porto University, Al. Prof. Hernani Monteiro, P-4200–319 Porto, Portugal2.Molecular Pathology and Forensic Biochemistry Laboratory, Centro de Investiga??o Interdisciplinar Egas Moniz, P-2825-084 Caparica, Portugal;Laboratório de Ciências Forenses e Psicológicas Egas Moniz, Campus Universitário–Quinta da Granja, Monte de Caparica, P-2825-084 Caparica, Portugal3.iNOVA4Health, CEDOC, NOVA Medical School,NMS, Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal
摘要：Epidemiological studies have reported an increased risk of Parkinson's disease (PD) development in amphetamine-type stimulant users during their lifetime (Garwood et al., 2006; Rumpf et al., 2017). Protein inclusions mainly composed of misfolded and aggregated α-synuclein are the pathological hallmark of PD and other disorders known as synucleinopathies.
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论文发表日期：2021-11-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 2213-2214 )