Boosting proteolytic pathways as a treatment against glycation-derived damage in the brain?
Allen Taylo1
Eloy Bejarano2
1.Laboratory for Nutrition and Vision Research,USDA Human Nutrition Research Center on Aging,Tufts University,Boston,MA,USA;Departments of Chemical and Molecular Biology and Ophthalmology,Tufts University School of Medicine,Boston,MA,USA;Friedman School of Nutrition and Science Policy,Tufts University,Boston,MA,USA2.Laboratory for Nutrition and Vision Research,USDA Human Nutrition Research Center on Aging,Tufts University,Boston,MA,USA;School of Health Sciences and Veterinary School,Universidad Cardenal Herrera-CEU,CEU Universities,Moncada,Valencia,Spain
摘要：The worldwide adaptation of a Western lifestyle is associated with the increased consumption of high glycemia diets and an increased prevalence of obesity, metabolic syndrome, and diabetes. These diets increase the risk for a plethora of age-related diseases including cerebrovascular, cardiovascular, and eye-related disorders, which all share a common pathogenic factor: the accumulation of advanced glycation end-products (AGEs) (Semba et al., 2010; Aragno and Mastrocola, 2017).
机标关键词：
论文发表日期：2022-02-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：3( 320-322 )