Heme as an inducer of cerebral damage in hemorrhagic stroke:potential therapeutic implications
Luiz Ricardo da Costa Vasconcellos1
Pedro Moreno Pimentel-Coelho2
1.Cellular Signalling and Cytoskeletal Function Laboratory,The Francis Crick Institute,London,UK2.Instituto de Biofísica Carlos Chagas Filho,Universidade Federal do Rio de Janeiro,Instituto Nacional de Ciência e Tecnologia em Medicina Regenerativa,Rio de Janeiro,RJ,Brazil
摘要：Intracerebral hemorrhage (ICH) consists of the rupture of a cerebral artery leading to bleeding into the surrounding parenchyma.This event has a primary phase of brain injury consisting of mechanical tissue damage due to the mass effect,followed by a secondary phase of brain injury triggered by the presence of blood components released at the site of bleeding(Bulters et al.,2018).Despite the high rates of mortality and morbidity from ICH,no effective treatment is available so far.
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论文发表日期：2022-09-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1961-1962 )