Synergy of human platelet lysate and laminin to enhance the neurotrophic effect of human adipose-derivedstem cells
Pietro G di Summa1
Srinivas Madduri2
1.Department of Plastic,Reconstructive and Hand Surgery,University Hospital of Lausanne,University of Lausanne,Lausanne,Switzerland2.Department of Surgery,Bioengineering and Neuroregeneration,University of Geneva, University Hospital Geneva,Geneva,Switzerland
摘要：Despite the spontaneous regenerative capacity of the peripheral nervous system, clinical nerve repair often results in poor functional recovery with the high socio-economic burden. In presence of peripheral nerve injuries and when distal nerve transfers are not possible, nerve autografts, are the solution of choice to cross a critical nerve gap. However, these are associated with donor site morbidity and offer only suboptimal functional recovery. Thus, the need to improve the rate of effective regeneration has directed research attention towards stem cell therapy and nerve tissue engineering.
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论文发表日期：2022-10-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：3( 2200-2202 )