Technological advances expand our knowledge of lysosomal dysfunction in neurodegeneration
Chase Chen
Yu Chen
Ellen Sidransky
Medical Genetics Branch,National Institutes of Health,National Human Genome Research Institute,National Institutes of Health,Bethesda,MD,USA
摘要：In the almost seven decades since the initial discovery of the lysosome as an organelle,our understanding of the role of lysosomes has greatly evolved.We now know lysosomal function encompasses far more than its traditionally described role as the cell's"garbage disposal",referring to its well-established catabolic function.Lysosomes are integral to maintaining cellular health and viability,and they act as a major signaling hub within the cell(Ballabio and Bonifacino,2020).
机标关键词：technologicalknowledgeneurodadvancesdegenerationdysfunctionexpandlysosomal
论文发表日期：2023-03-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 539-540 )