Prenatal and postnatal drug exposure: focus on persistent central effects
Giulia Costa1
Alexia E.Pollack2
1.Department of Biomedical Sciences,Section of Neuroscience,University of Cagliari,Cagliari,Italy2.Department of Biology,University of Massachusetts-Boston,Boston,MA,USA
摘要：Clinical studies indicate significant use of prescription, nonprescription and social/recreational drugs by women during pregnancy; however, limited knowledge exists about the detrimental effects that this practice may have on the developing central nervous system of the fetus. Importantly, fewexperimental and clinical data are available on how gestational exposure could exacerbate the effects of the same or a different drug consumed by the offspring later in life. The present review summarizes recent findings on the central toxicity elicited by several classes of drugs, administered prenatally and postnatally in experimental animals and humans, focusing on prescription and nonprescription analgesics, anti-inflammatory agents, alcohol and nicotine.
机标关键词：exposurecentralfocusdrugeffectspersistentpostnatalprenatal
论文发表日期：2023-08-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 1697-1702 )
英文信息