Pediatric GNAO1 encephalopathies: from molecular etiology of the disease to drug discovery
Vladimir L.Katanaev1
Jana Valnohova2
Denis N.Silachev3
Yonika A.Larasati2
Alexey Koval2
1.Translational Research Centre in Oncohaematology,Department of Cell Physiology and Metabolism,Faculty of Medicine,University of Geneva,Geneva,Switzerland;Institute of Life Sciences and Biomedicine,Far Eastern Federal University,Vladivostok,Russia2.Translational Research Centre in Oncohaematology,Department of Cell Physiology and Metabolism,Faculty of Medicine,University of Geneva,Geneva,Switzerland3.Translational Research Centre in Oncohaematology,Department of Cell Physiology and Metabolism,Faculty of Medicine,University of Geneva,Geneva,Switzerland;Institute of Life Sciences and Biomedicine,Far Eastern Federal University,Vladivostok,Russia;Department of Functional Biochemistry of Biopolymers,A.N.Belozersky Research Institute of Physico-Chemical Biology,Moscow State University,Moscow,Russia
摘要：Gαo is the major G protein in neurons, where it transduces signals from numerous G protein-coupled receptors (GPCRs) such as D2 dopamine, μ-opioid, M2 muscarinic, or α2-adrenergic receptors.
机标关键词：discoverymolecularcephnceplopahalopathence
论文发表日期：2023-10-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 2188-2189 )