Quite amusing stem cells: Muse cells
Molly Monsour1
Cesar V.Borlongan2
1.University of South Florida Morsani College of Medicine, Tampa, FL, USA2.Department of Neurosurgery and Brain Repair,University of South Florida, Morsani College of Medicine, Tampa, FL, USA
摘要：Stem cells may be the future of therapeutics for stroke due to their regenerative and immunomodulatory capabilities. Major barriers faced when employing stem cells, however, include faulty migration, low cell survival, and diminished proliferation. Multilineage-differentiating stress ensuring (Muse) cells, a subset of mesenchymal stem cells, overcome these barriers. Muse cells aid in neuroregeneration, have immense regenerative potential, and are pluripotent, non-tumorigenic, and immunomodulatory. In stroke specifically, these cells may restore an anti-inflammatory environment, regenerate damaged neurons, and integrate into the neuronal architecture. In fact, Muse cells may be aptly designed to ameliorate neurovascular unit damage following stroke and observed in other neuroinflammatory disorders.
机标关键词：cellsstemmuseamusingquite
论文发表日期：2023-11-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 2377-2378 )