Regulation of one-carbon metabolism may open new avenues to slow down the initiation and progression of Huntington's disease
Jiahua Xie
Farooqahmed S.Kittur
Chiu-Yueh Hung
Tomas T.Ding
Department of Pharmaceutical Sciences,Biomanufacturing Research Institute&Technology Enterprise,North Carolina Central University,Durham,NC,USA
摘要：Huntington's disease (HD) (OMIM 143100) is an autosomal dominant neurodegenerative disorder caused by a monogenic mutation in the huntingtin gene (HTT), which induces typical midlife onset and age-dependent progression with major symptoms including choreic movements, psychiatric disorders, and cognitive impairment (Gusella et al., 2021).
机标关键词：huntingtondownopenavenuesdiseaseinitiationmetabolismone-carbon
论文发表日期：2023-11-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 2401-2402 )