Repair and regeneration of peripheral nerve injuries that ablate branch points
JuliAnne E.Allgood1
George D.Bittner2
Jared S.Bushman1
1.Division of Pharmaceutical Sciences,University of Wyoming,Laramie,WY,USA2.Department of Neuroscience,The University of Texas at Austin,Austin,TX,USA
摘要：The peripheral nervous system has an extensive branching organization,and peripheral nerve injuries that ablate branch points present a complex challenge for clinical repair.Ablations of linear segments of the PNS have been extensively studied and routinely treated with autografts,acellular nerve allografts,conduits,wraps,and nerve transfers.In contrast,segmental-loss peripheral nerve injuries,in which one or more branch points are ablated so that there are three or more nerve endings,present additional complications that have not been rigorously studied or documented.This review discusses:(1)the branched anatomy of the peripheral nervous system,(2)case reports describing how peripheral nerve injuries with branched ablations have been surgically managed,(3)factors known to influence regeneration through branched nerve structures,(4)techniques and models of branched peripheral nerve injuries in animal models,and(5)conclusions regarding outcome measures and studies needed to improve understanding of regeneration through ablated branched structures of the peripheral nervous system.
机标关键词：regenerationbranchthatablateinjuriesnerveperipheralpoints
论文发表日期：2023-12-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 2564-2568 )
英文信息