Iron regulatory protein 1:the deadly switch of ferroptosis
Daniel A.Bórquez1
Pamela J.Urrutia2
1.Center for Biomedical Research,Faculty of Medicine,Universidad Diego Portales,Santiago,Chile2.Institute of Nutrition & Food Technology(INTA),Universidad de Chile,Santiago,Chile;Geroscience Center for Brain Health and Metabolism,Santiago,Chile
摘要:Ferroptosis,an iron-dependent cell death:Ferroptosis is a type of regulated necrosis,characterized by redox-active iron accumulation and increased free radical production derived by Fenton chemistry,that triggers oxidation of polyunsaturated fatty acids in phospholipids,loss of cellular membranes integrity,and leakage of intracellular contents.
机标关键词:ferroptosisproteinswitchdeadlyironregulatory
论文发表日期:2024-03-28
在线出版日期:2025-08-15(本平台首次上网日期,不代表文献的发表时间)
页数:2( 477-478 )
