Implications for brainstem recovery from studies in primates after sensory loss from arm
Jamie L.Reed
Hui-Xin Qi
Jon H.Kaas
Department of Psychology,Vanderbilt University,Nashville,TN,USA
摘要：For decades,researchers have known that when neurons lose their activating inputs,they can atrophy and even die.For example,removing sensory nerve inputs from the arm to the spinal cord after amputation or cutting the spinal nerves can shrink the post-synaptic target zones(e.g.,Woods et al.,2000).From touch receptors for the hand and arm,primary nerve afferents enter the spinal cord,and axons travel in the dorsal columns to target the cuneate nucleus(Cu)of the brainstem on the same side of the body(Figure 1).When sensory loss is unilateral,the overwhelming result is for the associated primary target zone to shrink in total size(cross-sectional area),as compared to the size of the opposite side.While this concept is widely accepted,many details about the factors that influence the shrinkage are not known.What are the effects of different types of sensory loss on the relative shrinkage?
机标关键词：recoverystudiesafterfromlossbrainstemimplicationsprimates
论文发表日期：2024-03-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 479-480 )