In vivo astrocyte reprogramming following spinal cord injury
Yannick N.Gerber1
Florence E.Perrin2
1.MMDN,University of Montpellier,EPHE,INSERM,Montpellier,France2.MMDN,University of Montpellier,EPHE,INSERM,Montpellier,France;Institut Universitaire de France(IUF),Paris,France
摘要：Harmful and helpful roles of astrocytes in spinal cord injury(SCI):SCI induce gradable sensory,motor and autonomic impairments that correlate with the lesion severity and the rostro-caudal location of the injury site.The absence of spontaneous axonal regeneration after injury results from neuron-intrinsic and neuron-extrinsic parameters.Indeed,not only adult neurons display limited capability to regrow axons but also the injury environment contains inhibitors to axonal regeneration and a lack of growth-promoting factors.
机标关键词：cordvivoastrocytefollowinginjuryreprogrammingspinal
论文发表日期：2024-03-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 487-488 )