Commentary on"Synchronized activity of sensory neurons initiates cortical synchrony in a model of neuropathic pain"
Lorenzo Di Cesare Mannelli
Carla Ghelardini
Department of Neuroscience,Psychology,Drug Research and Child Health-Neurofarba-Section of Pharmacology and Toxicology,University of Florence,Florence,Italy
摘要：In patients,as well as in animal models,hypersensitivity to external stimuli(hyperalgesia and allodynia)or spontaneous pain is often the first,and the most disabling,symptom of neuropathy(Davis et al.,2020).The increased activity of sensitive neurons drives pain development,making ion channel modulation a fundamental target for current pharmacotherapy as well as one of the most investigated by the R&D departments of pharmaceutical companies(Bennett et al.,2019).
机标关键词：synchronizedactivitymodelcommentarycorticalinitiatesneuronsneuropathic
论文发表日期：2024-04-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：1( 728 )