Soluble alpha-synuclein post-translational modifications:unexpected regulators of pathological alpha-synuclein amplification
Simran Kapila1
Yuhan Sun1
Chao Peng2
Shujing Zhang1
1.Department of Neurology,David Geffen School of Medicine,University of California,Los Angeles,CA,USA2.Department of Neurology,David Geffen School of Medicine,University of California,Los Angeles,CA,USA;Molecular Biology Institute,Brain Research Institute,Mary S.Easton Center for Alzheimer's Research,University of California,Los Angeles,CA,USA
摘要：The build-up of misfolded α-synuclein (α-syn) in the central nervous system is the pathological hallmark of a number of neurodegenerative diseases that are known as α-synucleinopathies. These include Parkinson's disease (PD), Parkinson's disease with dementia (PDD), dementia with Lewy body (LB), multiple system atrophy (MSA), and a subset of Alzheimer's disease.
机标关键词：postalpha-synucleinamplificationmodificationspathologicalregulatorssolubletranslational
论文发表日期：2024-05-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 959-960 )