Neurovascular unit on a chip:the relevance and maturity as an advanced in vitro model
Sujey Palma-Florez1
Anna Lagunas2
Mònica Mir3
1.Nanobioengineering Group,Institute for Bioengineering of Catalonia (IBEC) Barcelona Institute of Science and Technology (BIST),Barcelona,Spain;Department of Electronics and Biomedical Engineering,University of Barcelona,Barcelona,Spain2.Nanobioengineering Group,Institute for Bioengineering of Catalonia (IBEC) Barcelona Institute of Science and Technology (BIST),Barcelona,Spain;CIBER-BBN,ISCⅢ,Madrid,Spain3.Nanobioengineering Group,Institute for Bioengineering of Catalonia (IBEC) Barcelona Institute of Science and Technology (BIST),Barcelona,Spain;CIBER-BBN,ISCⅢ,Madrid,Spain;Department of Electronics and Biomedical Engineering,University of Barcelona,Barcelona,Spain
摘要：The brain is a high-energy demanding organ,consuming around 20％of the metabolic energy generated.To fulfill this demand,cerebral blood flow(CBF)supplies oxygen and glucose continuously through the intricate network of cerebral blood vessels.Although for many years brain activity and blood flow were conceived as independent processes,MRI-based functional brain imaging demonstrated that there is a coupling between them,leading to the concept of the neurovascular unit(NVU)to reflect their interplay(Raichle and Mintun,2006).
机标关键词：advancedvitrochipmodelmaturityneurovascularrelevanceunit
论文发表日期：2024-06-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1165-1166 )