Anoctamin 4 defines glucose-inhibited neurons in the ventromedial hypothalamus
Longlong Tu1
Yanlin He2
Yong Xu3
1.Children's Nutrition Research Center,Department of Pediatrics,Baylor College of Medicine,One Baylor Plaza,Houston,TX,USA2.Brain Glycemic and Metabolism Control Department,Pennington Biomedical Research Center,Louisiana State University,Baton Rouge,LA,USA3.Children's Nutrition Research Center,Department of Pediatrics,Baylor College of Medicine,One Baylor Plaza,Houston,TX,USA;Department of Molecular and Cellular Biology;Section of Endocrinology,Diabetes and Metabolism,Department of Medicine,Baylor College of Medicine,Houston,TX,USA
摘要：Glucose is the primary fuel source of the brain,and therefore glucose levels need to be tightly regulated and maintained within a small physiological range.Certainly,the body necessitates a stable supply of energy mainly provided by glucose for various bodily functions.High or low blood glucose levels would impair the physiological functions of various organs of the body.Prolonged high blood glucose(i.e.,hyperglycemia)would cause damage to the blood vessels,nerves,and other organs(e.g.,heart,kidneys,and eyes).Low blood glucose(i.e.,hypoglycemia)would undermine brain functions and lead to seizures,loss of consciousness,and other serious complications including death.
机标关键词：anoctaminglucosedefineshypothalamusinhibitedneuronsventromedial
论文发表日期：2024-06-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1177-1178 )