Insights on ZEB1-AS1:emerging roles from cancer to neurodegeneration
Stephana Carelli1
Federica Rey1
Erika Maghraby2
Cristina Cereda3
1.Pediatric Research Center "Romeo ed Enrica Invernizzi",Department of Biomedical and Clinical Sciences,University of Milan,Milan,Italy;Center of Functional Genomics and Rare Diseases,Department of Pediatrics,Buzzi Children's Hospital,Milan,Italy2.Pediatric Research Center "Romeo ed Enrica Invernizzi",Department of Biomedical and Clinical Sciences,University of Milan,Milan,Italy;Department of Biology and Biotechnology "L.Spallanzani",University of Pavia,Pavia,Italy3.Center of Functional Genomics and Rare Diseases,Department of Pediatrics,Buzzi Children's Hospital,Milan,Italy
摘要：Implications for IncRNAs in the central nervous system:Transcriptional dysregulation is a key contributor to the pathogenesis of a wide range of diseases and long non-coding RNAs(IncRNAs)are highly expressed in the nervous system.Indeed,amongst the over 50,000 IncRNAs expressed in the human genome,more than 40％are specifically expressed in the brain where their roles in brain development,neuron functions,maintenance,and differentiation,are becoming increasingly evident(Zhou et al.,2021).
机标关键词：insightsneurodcancerfromdegenerationemergingroles
论文发表日期：2024-06-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1187-1188 )