Modifying the progression of Parkinson's disease through movement interventions:multimodal quantification of underlying mechanisms
Manuel Bange
Damian Marc Herz
Dumitru Ciolac
Gabriel Gonzalez-Escamilla
Sergiu Groppa
Section of Movement Disorders and Neurostimulation,Department of Neurology,Focus Program Translational Neuroscience(FTN),University Medical Center of the Johannes Gutenberg-University Mainz,Mainz,Germany
摘要：Introduction:Parkinson's disease(PD)is the most common neurodegenerative movement disorder.The pathological hallmark is the progressive loss of dopaminergic neurons of the substantia nigra pars compacta,which is accompanied by widespread alterations in the structure and function of distributed brain networks.Together,these processes cause a variety of motor symptoms such as bradykinesia,rigidity,tremor,gait disorders,or difficulties in fine motor control(Bange et al.,2022).
机标关键词：quantificationparkinsonthroughdiseaseinterventionsmechanismsmodifyingmovement
论文发表日期：2024-08-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1651-1652 )