Oncostatin M:a love-hate relationship in neuroinflammation
Doryssa Hermans
Niels Hellings
Bieke Broux
University MS Center,Campus Diepenbeek,Diepenbeek,Belgium;Neuro-Immune Connections and Repair Lab,Department of Immunology and Infection,Biomedical Research Institute,Hasselt University,Diepenbeek,Belgium
摘要：Oncostatin M and multiple sclerosis:Every 5 minutes,someone in the world is diagnosed with multiple sclerosis(MS),a chronic inflammatory and degenerative disease of the central nervous system(CNS).MS appears in unpredictable episodes of symptoms,which are highly patient-dependent,but often include visual impairment,muscle weakness/spasms,fatigue,cognitive difficulties,and bladder,bowel,or sexual dysfunction.In severe cases,MS patients become wheelchair-bound due to paralysis.These symptoms are the result of a dysfunctional signal transduction from one neuron to another after the immune system has attacked the neuron's insulating myelin sheath.
机标关键词：relationshipeuroinflammationlove-hateoncostatin
论文发表日期：2024-12-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 2571-2572 )