Like a G6-nal:transcriptional control of G-protein coupled receptors during oligodendroglial development
Tim Aberle
Michael Wegner
Institut für Biochemie,Fried rich-Alexander-Universität Erlangen-Nürnberg,Erlangen,Germany
摘要：Multilayered control of myelination:Quick,saltatory conduction of action potentials along nerve fibers requires the electrical insulation of axons by myelinating glia.In the central nervous system,this role is taken up by oligodendrocytes.Oligodendrocytes are marked by the expression of the lineage determinants Sox10 and Olig2 and arise from oligodendrocyte precursor cells(OPCs)during embryonal stages.While the majority of OPCs differentiate into mature oligodendrocytes when nearby axonal segments require myelination,a small subpopulation of OPCs persist as a progenitor pool.
机标关键词：developmentcontrolliallikecoupledduringg-proteinoligodendroglia
论文发表日期：2025-07-27
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 2001-2002 )