Central role of altered phosphodiesterase 2-dependent signaling in the pathophysiology of cognition-based brain disorders
Asma Boulksibat
Alessandra Tempio
Barbara Bardoni
Institut de Pharmacologie Moléculaire et Cellulaire,CNRS UMR7275,Inserm U1323,Valbonne,France
摘要：The second messengers 3',5'-cyclic adenosine monophosphate(cAMP)and 3',5'-cyclic guanosine monophosphate(cGMP)modulate molecular pathways that are involved in a large variety of cellular processes.In the brain,these processes include neurogenesis,neuronal differentiation,activation and function of microglia,and synaptic plasticity,finally resulting in memory formation.
机标关键词：centralbrainrolediesiestphos2-dependentaltered
论文发表日期：2025-08-27
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 2302-2303 )