Nucleoside modified mRNA-lipid nanoparticles as a new delivery platform for the repair of the injured spinal cord
Krisztián Pajer
Tamás Bellák
Antal Nógrádi
Department of Anatomy,Histology and Embryology,Albert Szent-Györgyi Medical School,University of Szeged,Szeged,Hungary
摘要：Spinal cord injury and treatment opportunities:The adult mammalian spinal cord has a very limited capacity for spontaneous regeneration due to various intrinsic molecular and cellular factors.Although the spinal cord neurons have the capacity to regenerate their axons,the expression of growth inhibitory factors,lack or suppression of proper guidance cues,and profound inflammatory responses do not permit successful regeneration(Khyeam et al.,2021).
机标关键词：platformmodifiedcorddeliveryinjuredmrna-lipidnanoparticlesnucleoside
论文发表日期：2025-08-27
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 2311-2312 )