Cellular models of stress resistance may pave ways to fight neurodegenerative diseases
Thu Nguyen Minh Pham
Christian Behl
Institute of Pathobiochemistry,University Medical Center of the Johannes Gutenberg University,Mainz,Germany
摘要:Alzheimer's disease(AD),the most common form of neurodegeneration,is characterized by selective neuronal vulnerability and brain region-selective neuron demise.The entorhinal cortex and hippocampal CA1 projection neurons are at greater risk in AD whereas other regions display resistance to neurodegeneration.Interestingly,the cerebellum,a phylogenetically very old region,is affected only very late in the disease progression.
机标关键词:cellularneurodstressmodelsdegenerativediseasesfightpave
论文发表日期:2025-09-27
在线出版日期:2025-08-15(本平台首次上网日期,不代表文献的发表时间)
页数:2( 2579-2580 )
