Crosstalk between androgen signaling and the chemokine receptor CXCR4:a novel strategy to promote myelin regeneration
Marianne Bardy-Lagarde
Narimène Asbelaoui
Abdel Mouman Ghoumari
UMR1195,"Diseasesand Hormones of the Nervous System",Inserm and University Paris-Saclay,Kremlin-Bicêtre,France
摘要：Multiple sclerosis(MS)is the most common chronic disease of the central nervous system(CNS)in young adults and represents the first cause of severe handicap,originally non-traumatic(Oh et al.,2018).MS is characterized by the infiltration of auto reactive lymphocytes specific to myelin through the blood-brain barrier,which results in the appearance of inflammatory demyelinating lesions caused by the death of the central nervous system myelinating cells,oligodendrocytes(Oh et al.,2018).There is a prevalence sexual with a ratio of three times more affected women than men.
机标关键词：regenerationcrosstalkstrategyreceptorcxcr4betweennovelandrogen
论文发表日期：2025-09-27
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 2581-2582 )