Sex differences in aging and injured brain
Jordan N.Williamson1
Yuan Yang2
1.University of Illinois Urbana-Champaign,Grainger College of Engineering,Department of Bioengineering,Urbana,IL,USA2.University of Illinois Urbana-Champaign,Grainger College of Engineering,Department of Bioengineering,Urbana,IL,USA;Carle Foundation Hospital,Stephenson Family Clinical Research Institute,Clinical Imaging Research Center,Urbana,IL,USA;University of Illinois Urbana-Champaign,Beckman Institute for Advanced Science and Technology,Urbana,IL,USA;Northwestern University,Department of Physical Therapy and Human Movement Sciences,Chicago,IL,USA
摘要：Background:The prevalence,age of onset,and symptomatology of traumatic brain injury,stroke,and neurodegenerative diseases(such as Alzheimer's disease(AD),Parkinson's disease,amyotrophic lateral sclerosis,and Huntington's disease)differ substantially between males and females.The higher prevalence of these brain disorders has been attributed to females having a greater longevity compared with males.Since one of the greatest risk factors of acquired brain injury(such as stroke,traumatic brain injury caused by fall)and neurodegenerative disease is age,it would be reasonable to state that more females would live long enough to develop a brain disorder.However,a recent systematic review and meta-analysis shows that even when baseline data is adjusted for demographic covariates such as age,females continue to have worse rehabilitation outcomes and account for more deaths compared to males(Ali,2022).
机标关键词：brainagingdifferencesinjured
论文发表日期：2025-10-27
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 2901-2902 )