Iron-handling solute carrier SLC22A17 as a blood-brain barrier target after stroke
Xueqi Ren1
Wenlu Li2
1.Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province,School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou,Zhejiang Province,China2.Neuroprotection Research Laboratories,Departments of Radiology and Neurology,Massachusetts General Hospital,Harvard Medical School,Boston,MA,USA
摘要：The pathophysiology of ischemic stroke is complex and multifactorial,involving various forms of cell death such as apoptosis,autophagy,and necrosis.A recent study suggests that oxidative and inflammatory stress can induce ferroptosis,a specialized form of cell death characterized by the accumulation of lipid peroxides dependent on intracellular iron overload(Li and Jia,2023).
机标关键词：barrierstroketargetafterblood-braincarrieriron-handlingsolute
论文发表日期：2025-11-27
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：2( 3207-3208 )