Localization of Fluorescent Substance in Scatting Turbid Media: Simulation and Phantom Validation
LIAO Hong-en
WANG Shuai
Takehiro Ando
Etsuko Kobayashi
Ichiro Sakuma
摘要：We proposed a method to identify spatial position of fluorescent sub-stance in living body. With the assumption that cancerous lesion has been successfully targeted by a specific exogenous fluorescent probe, the objective of this study is to seek a straightforward and simple solution for localizing fluorescent material inside scattering turbid media. Our method enables estimation of horizontal position and depth of the flu-orescent substance. A fluorescence detection system and corresponding simulation method are also developed to evaluate the proposed method. The phantom experimental results showed that the fluorescence produced by the fluorescent substance in scattering medium that simulates the adipose tissue could be detected. The fluorescence localizing can provide more precision position information to surgeons as to whether resection of certain parts of stomach is necessary. This method is possible to be used in gastric cancer diagnosis, therefore helping to reduce over-resection.
机标关键词：
分类号：TN911.7(通信)
论文发表日期：2018-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 9-15 )
英文信息