Study on the Correlation between the Characteristics of Carotid Plaque and Ischemic Stroke
WANG Qian
LIU Si-bo
LONG An-ni
LIU Jing-zhe
ZHANG Xiao-wei
LI Lei
1.Department of Vascular Surgery and Radiology, the First Affiliated Hospital of Tsinghua University, Beijing 100016, China2.Department of Vascular Surgery and Radiology, the First Affiliated Hospital of Tsinghua University, Beijing 100016, China3.Department of Vascular Surgery and Radiology, the First Affiliated Hospital of Tsinghua University, Beijing 100016, China4.Department of Vascular Surgery and Radiology, the First Affiliated Hospital of Tsinghua University, Beijing 100016, China5.Department of Vascular Surgery and Radiology, the First Affiliated Hospital of Tsinghua University, Beijing 100016, China6.Department of Vascular Surgery and Radiology, the First Affiliated Hospital of Tsinghua University, Beijing 100016, China
摘要：Objective: To evaluate the correlation between MRI plaque characteris-tics and ischemic stroke in patients with carotid artery stenosis≤ 50％. Methods: From September 2014 to February 2016, 43 patients with carotid artery plaque with stenosis less than or equal to 50％ were selected by ultrasound. All patients were examined by black blood MRI. The correlation between MRI plaque characteristics and other risk fac-tors and ischemic stroke was evaluated by single factor and multi factor analysis. Results:The median follow-up time of all patients was 11.8 months. Kaplan Meier survival analy-sis showed that the median time of stroke free was significantly shorter in patients with intracoronary hemorrhage than in patients without intracoronary hemorrhage, which was 14.3 months and 18.6 months, respectively ( P=0.001);the median time of stroke free was also significantly shorter in patients with coronary heart disease than in patients without coronary heart disease, which was 12.1 months and 18.7 months, respectively ( P=0.029). Cox regression analysis showed that coronary heart disease (HR=27.4;95％CI, 1.6-464.3;P=0.022) and intraplaque hemorrhage (HR=18.2;95％CI, 2.7-123.3; P=0.003) were inde-pendent risk factors for ischemic stroke. Conclusion:In the patients with carotid artery stenosis ≤ 50％, plaque hemorrhage and coronary heart disease are independent risk factors of ischemic stroke.
机标关键词：
分类号：R743(神经病学与精神病学)
论文发表日期：2019-09-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：12( 93-104 )
英文信息