Correlation between Carotid Plaque Characteristics without Operative Indication and Ischemic Stroke
Qian Wang1
Sibo Liu1
Anni Long1
Jingzhe Liu2
Xiaowei Zhang2
Lei Li1
1.Department of Vascular Surgery,the First Affiliated Hospital of Tsinghua University,Beijing 100016,China2.Department of Radiology,the First Affiliated Hospital of Tsinghua University,Beijing 100016,China
摘要：Objective To access the correlations between characteristics of carotid plaque in MRI and ischemic stroke in patients with ≤50％ carotid artery stenosis. Methods A total of 43 patients with≤50％ carotid artery stenosis were selected for ul-trasound from September 2014 to February 2016. A further test using magnetic resonance (MR) black blood imaging exam-ination were carried out to distinguish the anatomy of the vessel as well the composition of the atherosclerotic plaque with re-markable details. The relationship between carotid plaque characteristics in MRI and other risk factors of patients with is-chemic stroke was analyzed by univariate and multivariate analysis. Results The mean follow-up time was 11. 8 months. During the follow-up period, 4 of the 43 individuals experienced an ipsilateral ischemic stroke. Kaplan-Meier survival a-nalysis showed the mean ischemic stroke free survival of patients with coronary heart disease ( CHD) was significantly shor-ter than that in patients without CHD, which were 12. 1 months and 18. 7 months respectively (P=0. 029). The mean is-chemic stroke free survival of patients with intra-plaque hemorrhage ( IPH) was significantly shorter than that in patients without IPH, which were 14. 3 months and 18. 6 months respectively (P=0. 001). COX regression analysis showed that coronary heart disease (HR=27.4;95％ CI, 1. 6-464. 3; P=0. 022) and IPH (HR=18. 2; 95％ CI, 2. 7-123. 3;P=0. 003) were independent risk factors for ischemic stroke. Conclusion For patients with carotid artery stenosis≤50％, IPH of carotid plaques and CHD are independent risk factors for ischemic stroke.
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论文发表日期：2020-06-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 17-24 )
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