Visualization Analysis of CRISPR Gene-editing Knowledge Map Based on CiteSpace
GAO Can1
WANG Rui2
ZHANG Lin3
YUE Chang-wu4
1.Key Laboratory of Microbial Drugs Innovation and Transformation,Medical College,Yan'an University,Yan'an Shanxi 716000,China;Non-coding RNA and Drug Discovery Key Laboratory of Sichuan Province,Chengdu Medical College,Chengdu Sichuan 610050,China2.Non-coding RNA and Drug Discovery Key Laboratory of Sichuan Province,Chengdu Medical College,Chengdu Sichuan 610050,China3.Department of Pharmacy,Shaoxing People's Hospital,Shaoxing Hospital,Zhejiang University School of Medicine,Shaoxing Zhejiang 312000,China4.Key Laboratory of Microbial Drugs Innovation and Transformation,Medical College,Yan'an University,Yan'an Shanxi 716000,China
摘要：CRISPR is an adaptive immune defense system found in bacteria and archaea that is resistant to heterologous invasive genetic material. Later studies showed that the CRISPR system can be used for gene editing. This study used the Web of Science database as a search object, then visually analyzed the literature related to CRISPR gene-editing technology with CiteSpaceV. The results show that publications had increased year by year. USA ranked first in terms of publications, China is second, but the centrality is very low. Doudna JA and Zhang F have made outstanding contributions. There are close connections between the internal institutions of the various states, but there are few links between the states. The hot spot and frontier are the application of CRISPR in animals, plants, detection, diagnosis, and clinical treatment.
机标关键词：knowledgecitespaceanalysiscrisprbasedgene-editingvisualization
分类号：R735.2(消化系肿瘤)
论文发表日期：2021-09-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：21( 118-138 )
英文信息