The Function of Surfeit 4 Gene in vivo
ZHAO Yan1
YU Hong2
1.Department of Pathology and Pathophysiology,Nantong University School of Medicine,Nantong Jiangsu 226007,China2.Department of Pathology,the Fifth Affiliated Hospital of Nantong University/Taizhou People's Hospital,Taizhou Jiangsu 225300,China
摘要：Surfeit 4(Surf 4),one of the identified housekeeping genes,was previously thought to encode a transmembrane protein that acts as a cargo receptor to maintain basic cellular functions.In recent years,Surf 4 gene is overexpressed in some types of cancer,involved in the exosome signaling pathway in gastrointestinal stromal tumors,and played the role of an oncogene in ovarian cancer stem cells.In this paper,we review the characteristics and protein localization of Surf 4 gene,as well as its possible physiological functions and pathogenesis in various diseases and cancers,expecting to discuss its clinical application value.
机标关键词：functiongenevivosurfeit
分类号：R782(口腔颌面部外科学)
论文发表日期：2022-06-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 79-86 )
英文信息