Profiles and predictors of onset based differences in vocal characteristics of adults with auditory neuropathy spectrum disorder(ANSD)
Prateek Lokwani
Prashanth Prabhu
Kavassery Venkateswaran Nisha
Department of Audiology,All India Institute of Speech and Hearing,Manasagangothri,Mysuru,570 006,India
摘要：Purpose:Onset-based differences are understudied in Auditory Neuropathy Spectrum Disorder(ANSD)in dimensions such as voice,which is addressed in the study.The study aimed to profile and predict the best metrics of onset-related differences in acoustic vocal characteristics of early and late-onset ANSD patients.Methods:31 participants(15 early and 16 late-onset)aged 15-30 years diagnosed with ANSD were included in the study.The sustained phonation of vowel/i/recorded by the participants using android based smartphones of selected configuration was sent over email to the experimenter.Acoustic pa-rameters(fundamental frequency,harmonic frequencies,jitter,shimmer,harmonic-to-noise ratio,cepstral peak prominence-CPP,and pitch sigma)were analysed using Praat software.Results:Results revealed significantly increased(p＜0.05)fundamental frequency along with decreased F2 and F3 of/i/in the early-onset ANSD compared to the late-onset group,which can be explained based on differences in the pathophysiology of the disorder.Although not statistically significant,mean per-turbations(jitter and shimmer),harmonic-to-noise ratio,cepstral peak prominence,and pitch sigma were more affected in the early-onset group,reflective of lowered auditory feedback and periodicity in their voice samples.Results of discriminant analysis marked the emergence of F2,F3,and CPP as the most sensitive metrics for onset-based group differences in voice characteristics.Conclusions:The findings from the study highlight the role of acoustical voice evaluation(especially CPP,F2&F3)in verifying the onset of ANSD disorder.The insights from the onset-based differences seen in vocal characteristics can indirectly help audiologists in deciding the management options for ANSD.
机标关键词：characteristicsprofilesspectrumvocalwithadultsansdauditory
论文发表日期：2022-12-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 218-225 )
英文信息