Transient decrease in sound tolerance levels following hearing deprivation in normal-hearing subjects
Eleazar Graterón1
Tricia Scaglione2
Shriya Airen2
Stefania Goncalves2
Sinay A.Ceballos1
David Baguley3
Juan A.Chiossone4
1.Fundación Venezolana de Otología,Clinical Research Group,Venezuela2.University of Miami,Department of Otolaryngology,USA3.University of Nottingham,Hearing Science,UK4.Fundación Venezolana de Otología,Clinical Research Group,Venezuela;University of Miami,Department of Otolaryngology,USA
摘要：Objective:To determine the circadian influence on sound sensitivity produced by temporal hearing deprivation in healthy normal human subjects.Design:Participants underwent bilateral earplugging before completion of anthropometry,the author's developed questionnaire,the Hamilton Anxiety and Depression Inventory,pure tone audiometry(PTA),stapedial reflex thresholds(SRT),distortion products otoacoustic emissions input/output(DPOAE-I/O),and uncomfortable loudness levels(ULLs).Afterward,the participants were randomly divided into group A,starting at 8:00 a.m.and finishing at 8:00 p.m.,and group B,starting at 4:00 p.m.and ending at 4:00 a.m.Serum cortisol levels and audiological test results were obtained at the beginning and end of the session and 24-h free urinary cortisol levels were measured.Study sample:Thirty healthy volunteers.Results:PTA was 2.68 and 3.33 dB HL in groups A and B,respectively,with no statistical difference between them.ULLs were significantly lower in group A compared to group B,with an average of 8.1 dB SPL in group A and 3.3 dB SPL in group B(p＜0.0001).A SRT shift was observed in group A,with no difference in group B,and a night shift in DPOAE-I/O in group B.Conclusions:Reduced loudness tolerance is demonstrated during daytime hearing deprivation in contrast to nighttime;this may be due to increased central gain in the awake cortex.
机标关键词：tolerancelevelssounddecreasedeprivationfollowingnormal-hearingsubjects
论文发表日期：2022-12-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 232-238 )
英文信息