Vestibular rehabilitation in cerebellar ataxia with neuropathy and vestibular areflexia syndrome(CANVAS)-A case report
R.G.Harrell1
A.R.Cassidy2
B.N.Klatt1
P.Hovareshti3
S.L.Whitney4
1.School of Health and Rehabilitation Sciences,Department of Physical Therapy,University of Pittsburgh,Pittsburgh,PA,15219,USA2.School of Health and Rehabilitation Sciences,Department of Physical Therapy,University of Pittsburgh,Pittsburgh,PA,15219,USA;Rehabilitation Institute,University of Pittsburgh Medical Center,Pittsburgh,PA,15219,USA3.BlueHalo,Intelligent Automation,Rockville,MD,20855,USA4.School of Health and Rehabilitation Sciences,Department of Physical Therapy,University of Pittsburgh,Pittsburgh,PA,15219,USA;Department of Otolaryngology,University of Pittsburgh Medical School,Pittsburgh,PA,15219,USA
摘要：Background and purpose:Cerebellar ataxia,neuropathy,and vestibular areflexia syndrome(CANVAS)is a neurodegenerative disease of the cerebellum.The disease progression is slow,with up to 25％of people diagnosed needing to use a wheelchair after 15 years from diagnosis.Vestibular symptoms arise from centrally-mediated ocular movement degradation and the reduced vestibular-ocular reflex functioning bilaterally.To date,no report has shown an improvement in VOR gain or gait outcome measures in someone with CANVAS after a course of vestibular physical therapy.
Case description:A 65-year-old male,Patient X,first noticed symptoms in his fourth decade of life and was diagnosed with(CANVAS)in his seventh decade.Patient X reported numbness and tingling in his hands and feet,decreased ability to perform daily activities,and several falls.
Intervention:Patient X completed a four-month course of vestibular physical therapy,including vestib-ular ocular reflex exercises,balance training,gait training,and the VestAid application for eye gaze compliance monitoring.The Vestaid application uses eyes and facial recognition software to record the percentage of time that the patient kept their eyes on the target.
Outcomes:After vestibular therapy,Patient X had a clinically meaningful improvement in gait speed:from 1.02 m/s to 1.13 m/s and in the Functional Gait Assessment from 20/30 to 27/30.Patient X's eye gaze compliance improved from a median of 43％(range 25-68％)to a median of 67％(58-83％).
Discussion:This case study demonstrates that vestibular rehabilitation improved eye gaze compliance and functional outcomes in a person living with CANVAS.
机标关键词：rehabilitationcanvasreportcasewithareflexiaataxiacerebellar
论文发表日期：2023-12-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：9( 199-207 )