Preliminary study of the role of inner ear proteins in vestibular neuritis
Rong Wang1
Weiwei Han2
Li Li3
Lulu Li3
Xiaoxia Liu3
Yunqin Wu3
Weinv Fan3
1.Department of Neurology,Ningbo No.2 Hospital,Ningbo,Zhejiang,315010,PR China;School of Health Science Center,Ningbo University,Ningbo,Zhejiang,315211,PR China2.Department of Rehabilitation,Ningbo No.2 Hospital,Ningbo,Zhejiang,315010,PR China3.Department of Neurology,Ningbo No.2 Hospital,Ningbo,Zhejiang,315010,PR China
摘要：Objective:To evaluate the plasma levels of the otoconial proteins,otoconin-90 and otolin-1,in individuals diagnosed with vestibular neuritis(VN)and determine the feasibility of using these proteins as biomarkers for VN.
Methods:In this preliminary study,30 patients diagnosed with VN and 70 healthy individuals were recruited and followed to confirm whether they had benign paroxysmal positional vertigo(BPPV)during the following time.The recorded data included measurements of height,weight,and history of diabetes mellitus or hypertension.Additionally,levels of plasma otoconin-90,and otolin-1 were measured and compared.
Results:The plasma concentrations of otoconin-90 and otolin-1 may not be significantly different between pa-tients with VN and healthy controls,nor among patients with BPPV secondary to VN and patients with VN without BPPV.
Conclusions:Plasma otoconin-90 and otolin-1 levels may not serve as biomarkers of acute VN episodes or predict BPPV occurrence secondary to VN.
机标关键词：studyroleinnerneuritispreliminaryproteinsvestibular
论文发表日期：2024-09-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：4( 140-143 )
英文信息