The Value of Quantitative Coronary Computed Tomography Angiography and Digital Subtraction Angiography in the Evaluation of the Coronary Artery Stenosis in Patients with Coronary Heart DiseaseAbstract:Objective To explore the value of coronary computed tomographic angiography(CCTA)and digital subtraction angiography(DSA)in evaluating the degree of coronary artery stenosis in coronary heart disease.Methods A retrospective analysis was conducted on 100 patients with suspected coronary heart disease admitted to Linyi Central Hospital from October 2022 to October 2023.All patients underwent CCTA and DSA.Using DSA results as the gold standard,we evaluated the diagnostic efficacy of CCTA for coronary artery stenosis in coronary heart disease,analyzed the nature of plaques under different degrees of coronary artery stenosis,and further analyzed the differences in examination parameters among patients with mild,moderate,and severe stenosis.Results The diagnostic accuracy of CCTA for coronary artery stenosis was 93.00%,with a sensitivity of 96.63%and specificity of 63.64%.The number of segments diagnosed as mild,moderate,and severe stenosis by DSA were 157,70,and 36,respectively.While the number of segments diagnosed as mild,moderate,and severe stenosis by CCTA were 152,73,and 38,respectively.Kappa analysis showed a high degree of consistency between the two methods.The CCTA examination revealed that calcified plaques and mixed plaques are more common in the mild stenosis group,while non-calcified plaques are more prevalent in the moderate stenosis group.However,the proportions of the three plaque types do not significantly differ in the severe stenosis group.In different grades of stenosis,as the degree of stenosis worsens,minimal lumen area and minimum lumen diameter decreased,while the proportion of area stenosis and diameter stenosis increased(P<0.05).Conclusion Quantitative coronary CT angiography is of great value in evaluating the degree of coronary artery stenosis in coronary heart disease and can provide valuable reference for clinical diagnosis and treatment.
Application of Cognitive Intervention based on Cross-Theoretical Model in Patients with Acute Ischemic Stroke Treated by Mechanical EmbolectomyAbstract:Objective To study the application effect of cognitive intervention based on cross-theoretical model in patients with acute ischemic stroke(AIS)treated by mechanical embolectomy.Methods Sixty AIS patients who received mechanical embolectomy in Nanping First Hospital from July 2022 to June 2024 were included in the study.They were divided into a control group(n=30)and a study group(n=30),by a random number table method.The control group was given routine intervention,while the study group was given cognitive intervention based on cross-theoretical model on the basis of routine intervention.The clinical indicators,health behavior,quality of life of two groups were compared.Results The postoperative oral intake time,time of getting out of bed,hospital stay of the research group were significantly shorter than those of the control group,and the scores of National Institute of Health Stroke Scale at 7 days after operation were significantly lower than those of the control group(P<0.05).After the intervention,the scores of the health promoting lifestyle profile-Ⅱ and the generic quality of inventory in the study group were higher than those in the control group(P<0.05).Conclusion Cognitive intervention based on cross-theoretical model can effectively improve the health behavior of patients treated with mechanical embolectomy in AIS,promote the improvement of neurological and cognitive functions,and improve the quality of life.
Correlation Analysis of Inflammatory Factor,Oxidative Stress Factor Expression and Alveolar Bone Resorption in Gingival Crevicular Fluid of Periodontitis PatientsAbstract:Objective To analyze the correlation between inflammatory factor,oxidative stress factor expression and alveolar bone resorption in gingival crevicular fluid of patients with periodontitis.Methods From May 2022 to May 2024,88 patients with PD admitted to the People's Hospital of Yunyang District of Shiyan City were selected as the study group.Additionally,88 healthy individuals who underwent physical examinations during the same period at the same hospital were selected as the control group.The differences in inflammatory factors,oxidative stress factors,and alveolar bone resorption indicators between the two groups of patients were compared,and the correlation analysis were performed.Results Aspartate-specific cysteine protease 1(Caspase-1),nod-like receptor protein 3(NLRP3),interleukin-1β(IL-1β),apoptosis-associated speck-like protein containing a CARD(ASC),interleukin-18(IL-18),receptor activator of nuclear factor-κB ligand(RANKL),Type I collagen pyridine cross-linked amino-terminal peptide(NTX),matrix metalloproteinase-9(MMP9),and superoxide dismutase(SOD)were higher than those of the control group(P<0.05).Runt-related transcription factor 2(Runx2),osteoprotegerin(OPG),malondialdehyde(MDA),reactive oxygen species(ROS)were lower than those of the control group(P<0.05).Pearson correlation analysis showed that Caspase1,NLRP3,IL-1β,ASC,IL-18,and SOD were positively correlated with RANKL,NTX,and MMP9(P<0.05),and negatively correlated with Runx2 and OPG(P<0.05).MDA and ROS were positively correlated with Runx2 and OPG(P<0.05),and negatively correlated with RANKL,NTX,and MMP9(P<0.05).Conclusion In patients with PD,the expression of inflammatory factors in gingival crevicular fluid is upregulated,oxidative stress levels are elevated,and the imbalance in the RANKL/OPG ratio leads to alveolar bone resorption.This may provide important insights into the pathogenesis and treatment strategies of PD.
Effects of Sensory and Perceptual Training Combined with Task-Oriented Exercise Rehabilitation on Sensory Integration and Static Postural Control in Children with Spastic Cerebral PalsyAbstract:Objective To study the effects of sensory and perceptual training combined with task-oriented exercise rehabilitation on sensory integration and static postural control in children with spastic cerebral palsy.Methods A total of 84 children with spastic cerebral palsy treated in Tianjin Children's Hospital from March 2023 to June 2024 were selected and divided into a control group and an observation group,with 42 cases in each group by a random number table method.The control group received sensory and perceptual training,while the observation group received task-oriented exercise rehabilitation on the basis of the control group.The clinical effect of the two groups was compared.Results After intervention,both groups showed increased scores on the Berg balance scale and 6-minute walk test distance,with the observation group having higher scores than the control group(P<0.05).Both groups showed decreased scores on the modified Ashworth scale,with the observation group having lower scores than the control group(P<0.05).Both groups showed increased scores on the gross motor function measure,with the observation group having higher scores than the control group(P<0.05).Conclusion After sensory and perceptual training combined with task-oriented exercise rehabilitation,the children with spastic cerebral palsy can significantly improve their sensory integration ability and balance function,and promote their recovery as soon as possible,with good therapeutic effect and high clinical value.
The Comparison of Short-Term Efficacy and Prognosis between Laparoscopic Radical Resection and Open Surgery for Liver CancerAbstract:Objective To compare the short-term efficacy and prognosis of laparoscopic radical resection and open surgery for patients with liver cancer.Methods Sixty patients with liver cancer admitted to Clinical Medical College of Shaanxi University of Chinese Medicine from January 2023 to March 2024 were selected and divided into a control group(n=30)and an observation group(n=30),by a random number table method.The control group was treated with open surgery,while the observation group was treated with laparoscopic radical resection of liver cancer.The perioperative indicators of the two groups of patients were compared.Results After surgery,the observation group had shorter operation time,postoperative exhaust time,postoperative extubation time,absolute bed rest time,hospitalization time,bowel sound recovery time,and defecation time than the control group(P<0.05).The levels of C-reactive protein,procalcitonin,interleukin-6,and tumor necrosis factor-α in the observation group were lower than those in the control group(P<0.05).The serum albumin of the observation group was higher than that of the control group,while the total bilirubin,alanine aminotransferase,and aspartate aminotransferase were lower than those of the control group(P<0.05).The levels of adrenaline,norepinephrine,and dopamine in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The short-term efficacy and survival prognosis of laparoscopic radical resection for liver cancer are superior to those of open surgery,with this advantage being manifested in various aspects such as postoperative recovery,inflammatory status,organ damage,and stress.
The Improvement of Huazhuo Jiangzhi Decoction on Symptoms,Obesity Status,and Blood Lipids in Patients with Mixed HyperlipidemiaAbstract:Objective To explore the therapeutic effect of Huazhuo Jiangzhi Decoction on patients with mixed hyperlipidemia.Methods The study subjects were all selected from the outpatient department of Cardiovascular Medicine at the First Affiliated Hospital of Guizhou University of Chinese Medicine.Sixty patients from June 2023 to August 2024 with mixed hyperlipidemia were enrolled as study subjects.The enrolled patients were divided into a control group and an observation group,with 30 patients in each group by random number table method.The control group received conventional western medicine treatment,while the observation group was treated with modified Huazhuo Jiangzhi Decoction.The traditional Chinese medicine symptom scores and improvement in blood lipids,and their effects on liver and kidney function were further compared between the two groups.Results After treatment,the observation group had significantly lower scores for traditional Chinese medicine symptoms such as obesity,limb fatigue,and abdominal distension compared to the control group(P<0.05).The body mass index,waist circumference,and hip circumference of the observation group were also significantly lower than those of the control group(P<0.05).The observation group had significantly lower levels of total cholesterol,triglyceride,and low-density lipoprotein,while high-density lipoprotein were higher than those of the control group(P<0.05).There were no significant differences in alanine aminotransferase,aspartate aminotransferase,creatinine,and blood urea nitrogen levels between the two groups(P>0.05).Conclusion For patients with mixed hyperlipidemia,Huazhuo Jiangzhi Decoction can effectively alleviate clinical symptoms and obesity,improve lipid metabolism,and has good safety.
The Effect of Early Bladder Function Training on the Recovery of Bladder Function and Pelvic Floor Muscle Strength in Patients after Cervical Cancer Radical SurgeryAbstract:Objective To investigate the effect of early bladder function training on the recovery of bladder function and pelvic floor muscle strength in patients after radical surgery for cervical cancer.Methods One hundred and forty patients with cervical cancer from January 2023 to December 2024 who underwent radical surgery in Fujian Medical University Affiliated Min Dong Hospital were selected as the research subjects,and divided into a control group(n=70)and an observation group(n=70),by a random number table method.The control group received routine nursing care,while the observation group received early bladder function training on the basis of the control group.The recovery of bladder function,changes in clinical related indicators,pelvic floor muscle strength level,and improvement of quality of life were compared between the two groups of patients.Results The observation group exhibited superior bladder function and bladder compliance indicators compared to the control group(P<0.05).Additionally,the observation group demonstrated improved postoperative pelvic floor muscle strength and quality of life scores compared to the control group(P<0.05).Conclusion Early bladder function training can improve the bladder compliance of patients after radical surgery for cervical cancer,shorten the time of indwelling catheter,promote the of pelvic floor muscle strength,and improve the bladder function and quality of life of patients.
Analysis of Risk Factors and Construction of Predictive Model for Implant Treatment in Patients with PeriodontitisAbstract:Objective To explore the influencing factors of implant failure in patients with periodontitis and construct a risk prediction model.Methods A total of 286 patients with periodontitis who underwent implant treatment in Min Dong Hospital Affiliated to Fujian Medical University from May 2020 to April 2022 were collected,and followed up until April 2025.According to the conditions after 3-year follow-up after implantation,they were divided into a failure group(n=62)and a success group(n=224).Results The proportions of age≥60 years old,diabetes,smoking history,failure to clean teeth regularly,osteoporosis,not brushing teeth after meals,and brushing time<3 minutes in the failure group were all higher than those in the successful group(P<0.05).Multivariate logistic regression analysis showed that age≥60 years old,diabetes,smoking history,irregular teeth cleaning,and osteoporosis were independent risk factors affecting dental implant failure in patients with periodontitis(P<0.05).ROC curve analysis showed that the AUC value,sensitivity and specificity of the comprehensive index constructed by independent risk factors in predicting dental implant failure in patients with periodontitis were 0.742,75.80%and 61.60%,respectively.Conclusion Age≥60 years old,diabetes,smoking history,failure to clean teeth regularly,and osteoporosis are independent risks affecting dental implant failure in patients with periodontitis.The risk prediction model constructed based on the above indicators has certain predictive value and can provide a reference basis for the early clinical identification of high-risk populations.
Correlation Study on the Risk of Local Recurrence after Surgery of Colorectal CancerAbstract:Objective To explore the influencing factors of local recurrence risk after colorectal cancer surgery.Methods The clinical data of 149 colorectal cancer patients admitted to Quanzhou First Hospital from January 2022 to January 2024 were retrospectively selected.All patients were followed up for 1 year after surgery,and they were divided into a recurrence group(n=31)and a non-recurrence group(n=118)according to whether local recurrence occurred during the follow-up period.The clinical data of two groups of patients were compared to screen the influencing factors of local recurrence after radical resection of colorectal cancer,and draw a receiver operating characteristic(ROC)curve to analyze the predictive value.Results There were statistically significant differences in age,TNM staging,intraoperative blood transfusion,and pathological margin status between the two groups(P<0.05).Multivariate logistic regression results showed that age,TNM stage,and pathological margin status were risk factors for local recurrence after radical resection of colorectal cancer(P<0.05).The combined AUC of each factor for local recurrence after radical resection of colorectal cancer was higher than that of single factor prediction(P<0.05).Conclusion Age,TNM stage and pathological margin status are all risk factors for local recurrence after colorectal cancer surgery.The combination of the three has a relatively high predictive value for local recurrence after colorectal cancer surgery.
Clinical Efficacy of Kangfuxin Liquid Combined with Mayinglong Hemorrhoid Ointment in the Treatment of External Hemorrhoid Surgery PatientsAbstract:Objective To reveal the clinical efficacy of Kangfuxin Liquid combined with Mayinglong Hemorrhoid Ointment in the treatment of patients with external hemorrhoid surgery.Methods A total of 108 patients who underwent external hemorrhoid surgery in Fujian Normal University Hospital from September 2022 to December 2024 were selected as the research subjects.They were divided into a control group and an observation group by a random number table method,with 54 patients in each group.The control group received external application of Kangfuxin solution after surgery,while the observation group received external application of Kangfuxin solution combined with Mayinglong Shexiang Hemorrhoids Ointment.The efficacy,wound healing,pain level,inflammatory factors,and quality of life were compared between the two groups.Results Two weeks after treatment,the total effective rate in the observation group was significantly higher than that in the control group(P<0.05).The scores of wound edema,wound granulation growth,and wound exudate in the observation group were significantly lower than those in the control group(P<0.01).The visual analogue scale scores in the observation group were significantly lower than those in the control group at 7 days and 2 weeks after treatment(P<0.05).The levels of IL-1β,IL-6,IL-8,IL-17,TNF-α,and MCP-1 in wound exudate of the observation group were significantly lower than those of the control group 1 week after treatment(P<0.05).Two weeks after treatment,all dimension scores of the SF-36 scale in the observation group were significantly higher than those in the control group(P<0.05).Conclusion Postoperative application of Kangfuxin Liquid combined with Mayinglong Hemorrhoid Ointment is more effective than monotherapy for external hemorrhoid patients.It can effectively reduce pain,inhibit inflammation,accelerate wound healing,and thus improve quality of life.
Exploration of the Eradication Effect of High-Dose Proton Pump Inhibitors Combined with Amoxicillin Dual Therapy on Helicobacter PyloriAbstract:Objective To investigate the therapeutic effect of high-dose proton pump inhibitors(PPIs)combined with amoxicillin in combination therapy for patients with Helicobacter pylori(HP).Methods One hundred and sixty cases of HP infection patients admitted to the Second People's Hospital of Jiangyin from May 2023 to May 2024 were randomly divided into a control group and a study group,with 80 cases in each group.The control group was treated with conventional quadruple therapy,while the research group used high-dose PPI combined with amoxicillin for treatment.The HP eradication rate,symptom relief,adverse reactions,and treatment compliance between two groups of patients were compared.Results There was no statistically significant difference in HP eradication rate between the two groups of patients(P>0.05).The relief time of various symptoms in the study group was lower than that in the control group(P<0.05).The incidence of adverse reactions in the research group was lower than that in the control group(P<0.05).The medication adherence of the study group was higher than that of the control group(P<0.05).Conclusion The dual therapy of high-dose PPI combined with amoxicillin has a similar HP eradication effect as conventional quadruple therapy,but its symptom relief is faster,the incidence of adverse reactions is lower,and the patient's medication compliance is higher.
The Effect of Ultrasonic Guided Visualized Acupotomy on Activity Ability of Lumbar Spine in Patients with Lower Back PainAbstract:Objective To explore the effect of ultrasound-guided visualized acupotomy on lumbar spine range of motion in patients with lower back pain.Methods Ninety patients with lower back pain admitted to the Second Affiliated Hospital of Qiqihar Medical College from January 2024 to December 2024 were collected and divided into a control group and an observation group,with 45 cases in each group by random number table method.The control group accepted lumbar traction,while the observation group accepted ultrasound-guided visualized acupotomy.The treatment effects of the two groups were compared.Results The VAS scores at 1 month and 3 months post-treatment,as well as the ODI scores at 3 months and 6 months post-treatment,were lower in the observation group than in the control group(P<0.05).The FRR values for the erector spinae muscles during extension,flexion,and dynamic muscle endurance were higher in the observation group than in the control group(P<0.05).Conclusion Patients with low back pain who undergo ultrasound-guided visualized acupotomy can experience better enhancement of lumbar muscle strength and myoelectric conduction,as well as reduced pain,thereby improving lumbar function.
The Effect of Suture Embracing Nice Knot Elastic Fixation on Postoperative Joint Function Recovery and Complications in Patients with Ankle Fracture and Tibiofibular InjuryAbstract:Objective To explore the application value of suture embracing Nice knot elastic fixation in patients with ankle fractures accompanied by tibiofibular injuries.Methods One hundred and twenty patients with ankle fractures and tibiofibular injuries in Mentougou District Hospital from January to December 2024 were selected and randomly divided into an observation group and a control group,with 60 patients in each group,by a random number table method.The control group accepted cortical bone screw fixation,while the observation group accepted suture wrapped Nice knot elastic fixation.The excellent rate,joint morphology and structure,and ankle joint function indicators were compared between the two groups.Results There were no statistically significant differences in operation duration,fracture healing time,intraoperative blood loss,time to ambulation,and hospital stay between the two groups(P>0.05).The time to full weight-bearing in the observation group was shorter than that in the control group(P<0.05).The excellent and good rate in the observation group was higher than that in the control group(P<0.05).Three months postoperatively,the levels of inferior tibiofibular joint space,medial joint space,and ankle mortise width difference in both groups decreased compared to pre-operative measurements,while the tibiofibular overlap increased compared to pre-operative measurements.However,there were no statistically significant differences between the groups(P>0.05).Three months postoperatively,the ankle joint function scores,dorsiflexion and plantarflexion degrees of the ankle joint in the observation group were higher than those in the control group(P<0.05).The incidence of complications in the observation group was lower than that in the control group(P<0.05).Conclusion For patients with ankle fractures accompanied by tibiofibular injuries,using suture wrapped Nice knot elastic fixation can help improve the surgical success rate,ankle joint function,perioperative conditions,and reduce the incidence of complications.
Effect of Whole-course Management Nursing for the Lymphoma Patients Undergoing ChemotherapyAbstract:Objective To explore the application effect of whole-course management nursing mode in lymphoma patients undergoing chemotherapy.Methods Ninety lymphoma patients who received chemotherapy treatment in the Hematology Department of Sanming First Hospital from January 2023 to November 2024 were selected as the study subjects.All patients were randomly divided into a routine group and a whole-course management group using a random number table method,with 45 patients in each group.The routine group implements routine nursing,while the whole-course management group implements whole-course management nursing.Compare the incidence of complications and adverse reactions and nursing satisfaction between two groups,and compare the negative emotions,psychological resilience,sleep quality,self-efficacy,and quality of life before and after intervention between the two groups.Results There was no significant difference in the scores of negative emotions,psychological resilience,sleep quality,self-efficacy,and quality of life between the two groups before intervention(all P>0.05).After intervention,the negative emotions,psychological resilience,sleep quality,self-efficacy,and quality of life scores of both groups were improved,and the scores of the above indicators in the whole-course management group were significantly better than those in the routine group after intervention(all P<0.05).The total incidences of complications and adverse reactions in the whole-course management group were significantly lower than those in the routine group,and the nursing satisfaction was significantly higher than that in the routine group(all P<0.05).Conclusion In lymphoma patients undergoing chemotherapy,the whole-course management nursing model can significantly improve the negative emotions,sleep quality and mental resilience of patients,and effectively reduce the occurrence of complications and adverse reactions,making it worth promoting and using.
Diagnostic Effect of CT Perfusion Imaging Combined with CT Angiography on Acute Ischemic StrokeAbstract:Objective To investigate the effect of computed tomography perfusion(CTP)and computed tomography angiography(CTA)in the diagnosis of acute ischemic stroke.Methods A total of 115 suspected acute ischemic stroke patients admitted to Tianjin Hongqiao Hospital from June 2019 to June 2024 were selected as the study subjects.All patients voluntarily underwent CTP,CTA,and digital subtraction angiography(DSA)examinations.Using DSA examination results as the gold standard,compare and analyze the diagnostic efficacy of CTP,CTA alone,and CTP combined with CTA examination,and analyze the imaging indicators of CTP examination.Results Out of 115 suspected patients with acute ischemic stroke,80 cases were diagnosed.Compared with CTP or CTA examinations alone,CTP combined with CTA examination had significantly higher diagnostic accuracy,specificity,and sensitivity,lower misdiagnosis and missed diagnosis rates(all P<0.05).The CTP examination results showed that there were significant differences in cerebral blood flow,cerebral blood volume,mean transit time,and peak time between the infarcted area and the semi dark area and the control area(P<0.05).Conclusion The use of CTP combined with CTA examination in patients with acute ischemic stroke has better diagnostic efficacy than using CTP or CTA examination alone,and is worthy of clinical promotion and use.
Application Effect of Steep Axis Corneal Relaxing Incision in Refractive Cataract SurgeryAbstract:Objective To explore the effect of steep axis corneal relaxing incisions in patients undergoing refractive cataract surgery.Methods A total of 180 patients who underwent refractive cataract surgery at Jian'ou Municipal Hospital of Fujian Province from May 2022 to May 2024 were selected and divided into an observation group and a control group,with 90 patients in each group,based on the different surgical incision positions.The observation group made the main incision on the steep meridian of the cornea and made a penetrating full-thickness transparent corneal incision on the opposite side.The control group only made incisions along the steep axis meridian of the cornea.Compare the corneal astigmatism,uncorrected visual acuity,and best corrected visual acuity before surgery,1 month after surgery,and 3 months after surgery between two groups.Results One month after surgery,the corneal astigmatism in both groups decreased compared to before surgery,and the observation group was significantly lower than the control group(P<0.05).There was no significant difference in corneal astigmatism between the observation group at 3 months after surgery and 1 month after surgery(P>0.05).The corneal astigmatism degree in the control group increased significantly at 3 months after surgery compared to 1 month after surgery(P<0.05).The corneal astigmatism degree of the observation group was significantly lower than that of the control group at 3 months after surgery(P<0.05).One month after surgery,both groups showed an improvement in uncorrected visual acuity and best corrected visual acuity compared to preoperative levels(P<0.05).There was no significant difference in uncorrected visual acuity and best corrected visual acuity between the two groups at 1 month after surgery(P>0.05).There was no significant difference in uncorrected visual acuity and best corrected visual acuity between the two groups at 3 months after surgery compared to 1 month after surgery(P>0.05).There was no significant difference in the uncorrected visual acuity and best corrected visual acuity between the two groups at three months after surgery(P>0.05).Conclusion For patients undergoing refractive cataract surgery,using a steep axis corneal relaxing incision can effectively correct corneal astigmatism,and the effect is more stable than using only the steep axis meridian as a single incision.It is worthy of promotion and application.
Application Effect of Personalized Nursing in Patients Treated with Coronary Stent ImplantationAbstract:Objective To explore the effect of personalized nursing in patients treated with coronary stent implantation.Methods A total of 150 patients with coronary heart disease who were received coronary stent implantation in the 951st Hospital of the PLA Ground Force from August 2023 to July 2024 were selected as the study subjects.All patients were randomly divided into a control group and a personalized group with 75 patients in each group by random number table.The control group received routine nursing,while the personalized group received personalized nursing.Compare the changes in vital signs during the perioperative period,surgical related indicators,nursing satisfaction,and negative emotions before and after nursing between two groups.Results At admission,there was no significant difference in heart rate,systolic blood pressure,and diastolic blood pressure between the two groups(all P>0.05).Immediately before surgery and 20 minutes after the start of surgery,the heart rate,systolic blood pressure,and diastolic blood pressure of the personalized group were significantly lower than those of the control group(all P<0.05).The personalized group had shorter surgical preparation time and operation time than the control group,and higher intraoperative cooperation than the control group(all P<0.05).After nursing,the scores of self-rating scales of anxiety and depression in both groups were lower than before nursing,and the personalized group had significantly lower scores of self-rating scales of anxiety and depression than the control group after nursing(all P<0.05).The nursing satisfaction scores of personalized group in all dimensions were significantly higher than those of the control group(all P<0.05).Conclusion Personalized nursing for patients undergoing coronary stent implantation can further improve negative emotions,reduce stress reactions,and shorten surgical time compared to routine nursing.It is worth promoting and using.
Effect of Moxifloxacin Combined with Carbocisteine in the Treatment of Community-acquired PneumoniaAbstract:Objective To explore the effect of moxifloxacin combined with carbocisteine in the treatment of community-acquired pneumonia(CAP).Methods A total of 150 patients with CAP who were treated in Changshu First People's Hospital from June 2021 to June 2024 were selected.All the patients were divided into a moxifloxacin group and a control group with 75 cases in each by different treatment plans.The moxifloxacin group was treated with moxifloxacin combined with carbocisteine,while the control group was treated with piperacillin sodium and tazobactam sodium combined with carbocisteine.The treatment effects,symptom disappearance time,severity of pneumonia and levels of inflammatory factors before and after treatment were compared between the two groups.Results The total effective rate of moxifloxacin group was significantly higher than that of control group(P<0.05).The recovery time of body temperature,disappearance of cough and sputum,normalization of blood routine,and disappearance of lung rales in the moxifloxacin group were significantly shorter than those in the control group(all P<0.05).Before treatment,there was no significant difference in the scores of pneumonia severity index(PSI),the levels of C-reactive protein(CRP),tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and procalcitonin(PCT)between the two groups(P>0.05).After treatment,the scores of PSI and the levels of CRP,TNF-α,IL-6,and PCT in both groups were lower than before treatment,and the levels of these indicators in the moxifloxacin group were significantly lower than those in the control group after treatment(all P<0.05).Conclusion For patients with CAP,treatment with moxifloxacin combined with carbocisteine on the basis of symptomatic treatment has a good therapeutic effects,can promote patient recovery,and is worthy of clinical promotion and use.
Analysis of Disease Composition and Changing Trends of Inpatients in the Otolaryngology Department of a Large Tertiary Hospital in Eastern Inner MongoliaAbstract:Objective Analyze the disease composition and trends of inpatients in the otolaryngology department of a large tertiary hospital in eastern Inner Mongolia Autonomous Region over the past decade.Methods The clinical data of inpatients in the otolaryngology department of a large tertiary hospital in eastern Inner Mongolia Autonomous Region from June 1st,2013 to May 31st,2022 were collected in an anonymized manner.Based on the main diagnosis,according to the 10th edition of the International Statistical Classification of Diseases and Related Health Problems(ICD-10),the medical records were standardized and organized by using Excel 2022 software.Stratified by hospitalization years,age,gender,and ethnicity,the epidemiological descriptive analysis on the composition and changes of the top ten ear,nose,and throat diseases were analyzed using SPSS 26.0 software.Results A total of 17,367 patients'clinical data were collected,among which the top ten diseases in terms of patient numbers were chronic tonsillitis(19.39%),sudden idiopathic hearing loss(8.84%),sinusitis(8.45%),nasal septum deviation(7.45%),adenoid hypertrophy(7.39%),vocal cord polyps(5.55%),nasal bone fractures(3.82%),nasal polyps(3.56%),preauricular fistula(2.24%),and sleep apnea(2.20%).The disease spectrum has changed over the past decade,but the overall disease structure is relatively stable,with the number of patients with chronic tonsillitis basically ranking first in the disease spectrum over the years.The average age of patients is(32.44±22.59)years old,with the highest proportion of patients aged≤18 years old being the largest.The prevalence of otorhinolaryngological diseases varied among different age groups.The number of male patients(61.18%)is higher than that of females(38.82%),and chronic tonsillitis ranked first in the case number among both genders.The Mongolian ethnic group accounts for 20.95%,the Han ethnic group accounts for 74.30%,and other ethnic groups account for 4.74%.The order of diseases varies among different ethnic groups,with chronic tonsillitis ranking first.Conclusion Chronic tonsillitis is the main type of disease among hospitalized patients in the otolaryngology department of the hospital,and should be given special attention.Corresponding prevention and treatment measures should be taken,with a focus on protecting adolescent patients aged≤18 years old.Meanwhile,in conjunction with the disease spectrum,effective preventive and health care activities in otolaryngological disease should be implemented,and health medical resources should be allocated rationally.
Clinical Effects of Ear Scraping Therapy for Chronic Insomnia based on Polysomnography TechnologyAbstract:Objective To explore the clinical effects of ear scraping therapy for chronic insomnia based on polysomnography(PSG)technology.Methods A total of 100 patients with chronic insomnia who were treated at Weifang Hospital of Traditional Chinese Medicine from April 2022 to April 2024 were included as research objects.They were randomly divided into a control group and a study group with 50 patients in each group.The control group received conventional medication treatment,while the study group received ear scraping therapy on the basis of the control group treatment.Both groups were continuously treated for 10 days,and the sleep status of the two groups was monitored by PSG before and after treatment.The subjective sleep experience(Pittsburgh sleep quality index),quality of life,polysomnography results and treatment satisfaction of the patients in both groups before and after treatment were compared.Results After treatment,the Pittsburgh sleep quality index score of the study group was significantly lower than that of the control group,and the quality of life score was significantly higher than that of the control group(all P<0.05).After treatment,the PSG indicators in the study group were significantly better than those in the control group(all P<0.05).The overall treatment satisfaction in the study group was significantly higher than that in the control group(P<0.05).Conclusion On the basis of conventional medication treatment,chronic insomnia patients using ear scraping therapy based on PSG technology can have enhanced subjective sleep experience,prolonged sleep time,improved sleep quality and quality of life.It is worth promoting and using.