Evaluation of the Efficacy of Siji Antiviral Decoction Combined with Interferon in the Treatment of Adenovirus Pneumonia in Children

doi:10.16458/j.cnki.1007-0893.2025.20.020

Abstract：Objective: To investigate the clinical efficacy of Siji Antiviral Decoction combined with interferon in the treatment of adenovirus pneumonia in children. Methods: A total of 60 children with adenovirus pneumonia admitted to Jiujiang Maternal and Child Health Hospital from January 2023 to January 2025 were selected as the study subjects. They were randomly divided into a control group (interferon + conventional treatment) and an observation group (Siji Antiviral Decoction + interferon + conventional treatment), with 30 cases in each group. The clinical symptoms relief, absorption time of pulmonary shadows, laboratory indicators before and after treatment, clinical efficacy, and incidence of adverse reactions were compared between the two groups. Results: The fever relief time and cough relief time of the observation group were shorter than those of the control group, with statistically significant differences (P < 0.05). The absorption time of pulmonary shadows in the observation group was shorter than that in the control group, with statistically significant differences (P < 0.05). After treatment, the improvement in white blood cell count and serum C-reactive protein (CRP) levels in the observation group was better than that in the control group, with statistically significant differences (P < 0.05). The total effective rate of treatment in the observation group was higher than that in the control group, with statistically significant differences (P < 0.05). There was no statistically significant difference in the total incidence of adverse reactions between the two groups (P > 0.05). Conclusion: Siji Antiviral Decoction combined with interferon can promote symptom relief in children with adenovirus pneumonia, improve imaging indicators, inhibit inflammatory responses, enhance treatment effectiveness, and does not increase adverse reactions.