Effects of high power pulse microwave on the changes of myocardial enzyme spectrum
Abstract：AIM:To study the effects of high power pulse microwave(HPPM) on myocardial enzyme spectrum of serum. METHODS:Thirty experimental dogs and first generational suckling rats cultured in vitro were selected and the concentration of aspartate aminotransferase(AST),lactic dehydrogenase(LDH),lactic dehydrogenase isoenzyme(LD-1),creatine kinase(CK),creatine kinase isoenzyme(CK-mb), hydroxybutyric dehydrogenase(HBDH) and alkaline phosphatase(ALP) in the serum and medium were assayed. RESULTS:Myocardial enzyme spectrum disturbance occurred after HPPM irradiation, mostly was the decrease in enzymic activity.Most sensitive enzyme in experimental dog was CK,which continuously decreased significantly from 6 h to 1 month after irradiation,with the CK value of(796.9± 756.70),(287.8± 274.87),(367.2± 241.16), (324.4± 128.81), (336.5± 152.36),(257.5± 105.86),and(165.8± 99.00) mmol/L respectively representing 6 ,24 h,3 d,1 week,2 weeks and 1 month after irradiation(t=2.67- 4.77,P< 0.01).Most myocardial enzymes in the medium decreased to the lowest level after 0 to 1 h of irradiation and most of them returned to normal level at 24 h after irradiation, and the enzymic activities increased significantly at 48 h. CONCLUSION:HPPM irradiation can markedly affect the myocardial enzymic activities in myocardial cells of experimental animals.
Machine-generated Keywords：
Publication Date：2004-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 1154-1155 )