Intestinal involvement in scleroderma: Clinical characteristic of 11 cases
CHEN Ning
LIN Leng
YAN Qing
LIN He
Abstract：Objective To investigate the clinical characteristic of intestinal involvement in patients with scleroderma. Methods Clinical data of scleroderma with intestinal involvement admitted to our hospital from July 2007 to July 2017 were analyzed retrospectively.Results The age of patients was 13-64 (38.0 ± 18.0) years. It took 4 years from the diagnosis of scleroderma to intestinal involvement presentations. Two of the 11 patients had gastrointestinal symptoms as the primary mani-festation. Of the 11 patients,7 patients were pseudo-obstruction,3 patients were intestinal ulcer,1 patient was protein losing enteropathy. 11 patients were treated with acid,parenteral nutrition,somatostatin and other symptomatic treatment according to the diagnosis. 8 cases were treated with medium to large doses of glucocorticoid combined with cyclophosphamide. 9 cases were improved and discharged. The patient's condition was stable so far, and 2 cases were lost of follow up.Conclusion Scleroderma associated with a higher incidence of bowel involvement,severe intestinal involvement can influence the prognosis of patients,with early gastrointestinal symptoms in patients with scleroderma should be examined when necessary, in order to facilitate the early diagnosis of intestinal disease diagnosis and intervention.
Keywords：SclerodermaIntestinal involvementClinical characteristic
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 412-415 )